Management of Acute Renal Failure in Children


Haemolytic uraemic syndrome

In haemolytic uraemic syndrome there is evidence of intravascular haemolysis owing to microangiopathy with fragmentation of red cells (click here for picture), a low serum haptoglobin concentration and a marginally raised serum indirect bilirubin concentration.  Patients with this syndrome differ from those with other causes of renal failure in their ability to mount a reticulocyte response.  The platelet count is reduced by consumption in microthrombi.  There is no association with autoimmune haemolytic anaemia.

Link

http://emedicine.medscape.com/article/982025-overview

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