Clinical features:

Hypokalaemia
Renal Na⁺ and Cl^- wasting
Reduced ECF volume
Metabolic alkalosis
Hyperrenninaemia
Hypomagnesaemia
Hypocalcuria
Normal response to ADH

Molecular lesion:

Loss of function of the sodium chloride cotransporter (NCCT) in the apical membrane of the early distal convoluted tubule.  This is the site of action of thiazide diuretics.